By Professor Hans-Dieter Rott MD (auth.), Professor Hans-Dieter Rott MD (eds.)
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Additional resources for Bioeffect: Literature Reviews 1980–1987
Sabbagha (1981) Hum Genet 59: 221-226 This in vitro study reports experiments with human lymphocytes in G1 and S cell cycle phase, which are exposed to ultrasound (US) in an experimental arrangement designed to simulate the sonographic and special conditions of the fetus in utero. 5 MHz. 5-20 min. 1 exchanges/cell. 001 for 60- and 90-min experiments). As a second interesting finding, variances are also increased. The experimental procedure and the cytogenetic techniques are given in detail, and the SeE scoring was done blind.
A similar intense low frequency ultrasound field was used by P. Schmidt, E. Rosenfeld and 1. Fischer to increase the porosity of 1-mm diameter polystyrene spheres so as to improve their efficiencies as a carrier matrix onto which the Strasbourg, May 1984. 47 enzyme a-amylase was immobilised. 65 MHz ultrasound and observed a small increase in the reaction rate which was assumed to have been caused by some form of radiation pressure or acoustic microstreaming mechanism which accelerated diffusion processes ("The influence of ultrasound on matrix-bound enzymes").
Therefore, it is unlikely that diagnostic exposures of ultrasound would cause the formation of platelet micro emboli unless the irradiated blood contained pre-existing gas bubbles and was also in a hypercoagulable state. Dubrovnik-Cavtat, May 1981. 45 Absence of an effect of diagnostic ultrasound on sister chromatid exchange induction in human lymphocytes in vitro M. W. Miller, S. Wolff, R. Fuilly, C. Cox, E. L. Carstenson (1983) Mutat Res 120: 261-268 This paper reports in vitro experiments with cultured human lymphocytes which were irradiated with a focused pulsed diagnostic ultrasound beam (30 min, 2 MHz, l11S burst duration, 1000 Hz pulse repetition rate, 100 W/cm2 space peak time peak (SPTP) intensity).